منابع مشابه
Bactericidal action of streptomycin and comparison with spectinomycin in heterozygotes of Escherichia coli.
Str(s)/str(r) heterozygotes of Escherichia coli K-12 are shown to be sensitive to the lethal as well as the inhibitory action of streptomycin. The rate of killing was lower in heterozygotes than in sensitive homozygotes, and among heterozygotes it was lower in those with a higher proportion of resistant ribosomes. These strains also differed, in a parallel manner, in the kinetics of inhibition ...
متن کاملThe action of streptomycin.
Previous papers (Umbreit, 1949; Oginsky, Smith, and Umbreit, 1949) have presented data showing that one of the actions of streptomycin on a sensitive Escherichia coli strain was to inhibit the oxalacetate-pyruvate reaction. It was admitted that the exact nature of this reaction was not known and that methods for its measurement were somewhat indirect. At about the time these papers were publish...
متن کاملBactericidal Action of Histone
The arginine-rich fraction of calf thymus histone (histone B) exerts bactericidal activity on various coliform bacilli and micrococci under certain conditions in vitro. Final concentrations of less than 1 microg. histone per ml. kill susceptible microbes without detectable morphological alteration or lysis. Among the microorganisms highly susceptible to histone are Escherichia, Salmonella, Shig...
متن کاملStreptomycin Action and Anaerobiosis.
The question was asked whether the insensitivity to dihydrostreptomycin and streptomycin exhibited by facultatively anaerobic organisms growing strictly anaerobically could be due entirely to the lack of an anaerobic mechanism for the uptake of these antibiotics. A technique is described here which allows exposure of Escherichia coli B to dihydrostreptomycin, under conditions which are known to...
متن کاملMacromolecular Synthesis and the Bactericidal Effect of Streptomycin.
Rosenkranz, Herbert S. (Columbia University, New York, N.Y.). Macromolecular synthesis and the bactericidal effect of streptomycin. J. Bacteriol. 87:606-603. 1964.-Hydroxylamine, a bacteriostatic agent which inhibits deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein synthesis, interferes with the lethal action of streptomycin on growing cells of Escherichia coli. The addition of ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1948
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4547.382